Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP, isocitrate, and calcium(2+)

PDB ID: 1T0L
Gene source organism: Homo sapiens
Expression organism: Escherichia coli BL21(DE3) Deposition date: 2004-04-10
Classification: OXIDOREDUCTASE
Keywords: Rossmann fold, NADP, isocitrate, calcium, quaternary complex, Oxidoreductase
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.41
R-value: 0.214
Metal site idBound amino acidsBound ligands IDs
1T0L-CA-1 D2 ASP A.275 ASP B.252 HOH A.1763 ICT A.1616
1T0L-CA-2 D2 ASP A.252 ASP B.275 HOH B.1897 ICT B.1617