Structural and biochemical analysis of human pathogenic astrovirus serine protease at 2.0 Angstrom resolution

PDB ID: 2W5E
Gene source organism: HUMAN ASTROVIRUS 1
Expression organism: ESCHERICHIA COLI Deposition date: 2008-12-10
Classification: HYDROLASE
Keywords: COILED COIL, TRANSMEMBRANE, THIOL PROTEASE, RNA REPLICATION, RIBOSOMAL FRAMESHIFTING, SERINE PROTEASE, CATALYTIC TRIAD, PROTEASE, MEMBRANE, HYDROLASE, ANTIVIRAL, ASTROVIRUS
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.0
R-value: 0.234
Metal site idBound amino acidsBound ligands IDs
2W5E-CD-1 E1H1 GLU B.474 HIS A.-4
2W5E-CD-2 E1H1 GLU A.474 HIS B.-4
2W5E-CD-3 E1H1 GLU D.474 HIS C.-4
2W5E-CD-4 E1H1 GLU C.474 HIS D.-4
2W5E-CD-5 E1H1 GLU F.474 HIS E.-4
2W5E-CD-6 E1H1 GLU E.474 HIS F.-4