Crystal structure of the human nuclear membrane zinc metalloprotease ZMPSTE24 mutant (E336A) in complex with a synthetic CSIM tetrapeptide from the C-terminus of prelamin A

PDB ID: 2YPT
Gene source organism: HOMO SAPIENS
Expression organism: SPODOPTERA FRUGIPERDA Deposition date: 2012-11-01
Classification: HYDROLASE/PEPTIDE
Keywords: HYDROLASE-PEPTIDE COMPLEX, M48 PEPTIDASE, INTEGRAL MEMBRANE PROTEIN, PRELAMIN A PROCESSING, AGEING, PROGERIA
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 3.8
R-value: 0.2625
Metal site idBound amino acidsBound ligands IDs
2YPT-ZN-1 E1S1 GLU D.415 SER H.662