Discovery of Novel Uracil Derivatives as Potent Human dUTPase Inhibitors

PDB ID: 3ARA
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2010-11-25
Classification: Hydrolase/Hydrolase inhibitor
Keywords: Hydrolase, Magnesium Binding, Hydrolase-Hydrolase inhibitor complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.7
R-value: 0.21365
Metal site idBound amino acidsBound ligands IDs
3ARA-MG-1 E3 GLU A.135 GLU B.135 GLU C.135 HOH B.168