Crystal structure of the catalytic domain of Botulinum neurotoxin serotype a with a snap-25 peptide

PDB ID: 3DDA
Gene source organism: Clostridium botulinum
Expression organism: Escherichia coli Deposition date: 2008-06-05
Classification: HYDROLASE
Keywords: BOTULINUM NEUROTOXIN TYPE A, BOTOX, CATALYTIC DOMAIN, ENDOPEPTIDASE, SYNTAXIN, BIO-WARFARE AGENT, HYDROLASE, METAL-BINDING, METALLOPROTEASE, PROTEASE, SECRETED, TRANSMEMBRANE, ZINC, ENZYME-SUBSTRATE COMPLEX, Pharmaceutical, Alternative splicing, Cell junction, Coiled coil, Lipoprotein, Palmitate, Phosphoprotein, Synapse, Synaptosome
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.5
R-value: 0.183
Metal site idBound amino acidsBound ligands IDs
3DDA-ZN-1 H2Q1 GLN B.197 HIS A.223 HIS A.227