Crystal structure of human insulin degrading enzyme in complex with transforming growth factor-alpha

PDB ID: 3E50
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2008-08-12
Classification: Hydrolase/Hormone
Keywords: IDE, TGF-ALPHA, Cytoplasm, Hydrolase, Metal-binding, Metalloprotease, Polymorphism, Protease, Zinc, Cell membrane, EGF-like domain, Glycoprotein, Growth factor, Lipoprotein, Membrane, Mitogen, Palmitate, Secreted, Transmembrane, Hydrolase-Hormone COMPLEX
Technique: X-RAY DIFFRACTION
Assembly: 2
Resolution: 2.3
R-value: 0.1907
Metal site idBound amino acidsBound ligands IDs
3E50-ZN-1 E1H1 GLU B.189 HIS D.12