Structure of Human DNA Polymerase Iota complexed with N2-ethylguanine and incoming TTP

PDB ID: 3EPI
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2008-09-29
Classification: TRANSFERASE/DNA
Keywords: DNA pol iota, lesion bypass, N2-ethylguanine, DNA damage, DNA repair, DNA replication, DNA synthesis, DNA-binding, DNA-directed DNA polymerase, Magnesium, Metal-binding, Mutator protein, Nucleotidyltransferase, Nucleus, Schiff base, Transferase, TRANSFERASE-DNA COMPLEX
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.9
R-value: 0.23632
Metal site idBound amino acidsBound ligands IDs
3EPI-NA-1 C1I2K1 DC B.12 ILE A.239 ILE A.242 LYS A.237
3EPI-NA-2 C1I2K1 DC B.12 ILE A.239 ILE A.242 LYS A.237