Design of an insulin analog with enhanced receptor-binding selectivity. Rationale, structure, and therapeutic implications

PDB ID: 3FQ9
Gene source organism: None
Expression organism: None Deposition date: 2009-01-07
Classification: HORMONE
Keywords: receptor-binding, insulin design, rational, therapeutic implication, Carbohydrate metabolism, Cleavage on pair of basic residues, Diabetes mellitus, Disease mutation, Glucose metabolism, Hormone, Pharmaceutical, Secreted
Technique: X-RAY DIFFRACTION
Assembly: 5
Resolution: 1.35
R-value: 0.198
Metal site idBound amino acidsBound ligands IDs
3FQ9-ZN-1 H3 HOH B.32