Crystal Structure of Human Dual Specificity Protein Kinase (TTK) in complex with a pyrimido-diazepin ligand

PDB ID: 3H9F
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2009-04-30
Classification: TRANSFERASE
Keywords: TTK, hMPS1, PYT, ESK, kinase, Dual Specificity, phosphotyrosine picked threonine kinase, SGC, Structural Genomics Consortium, ATP-binding, Nucleotide-binding, Phosphoprotein, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.6
R-value: 0.207
Metal site idBound amino acidsBound ligands IDs
3H9F-MG-1 X2 TPO A.675 TPO A.676
3H9F-MG-2 X2 TPO A.675 TPO A.676
3H9F-MG-3 X2 TPO A.675 TPO A.676
3H9F-MG-4 X2 TPO A.675 TPO A.676