Crystal structure of intermediate affinity I domain of integrin LFA-1 with the Fab fragment of its antibody AL-57

PDB ID: 3HI6
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2009-05-19
Classification: cell adhesion/immune system
Keywords: integrin, I domain, Fab, ligand mimetic antibody, cell adhesion, Alternative splicing, Calcium, Disulfide bond, Glycoprotein, Magnesium, Membrane, Polymorphism, Receptor, Transmembrane, cell adhesion-immune system COMPLEX
Technique: X-RAY DIFFRACTION
Assembly: 3
Resolution: 2.3
R-value: 0.17
Metal site idBound amino acidsBound ligands IDs
3HI6-MN-1 D1S2T1 ASP H.101 HOH A.4 HOH H.223 SER A.139 SER A.141 THR A.206
3HI6-MN-2 D1S2T1 ASP X.101 HOH B.1 HOH X.222 SER B.139 SER B.141 THR B.206