Crystal structure of human Enterovirus 71 in complex with the uncoating inhibitor GPP4

PDB ID: 4CDW
Gene source organism: ENTEROVIRUS A71
Expression organism: CHLOROCEBUS AETHIOPS Deposition date: 2013-11-06
Classification: VIRUS
Keywords: VIRUS, HAND-FOOT-AND-MOUTH DISEASE, ENTEROVIRUS UNCOATING, INHIBITOR
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.8
R-value: 0.283
Metal site idBound amino acidsBound ligands IDs
4CDW-NA-1 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-2 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-3 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-4 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-5 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-6 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-7 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-8 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-9 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-10 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-11 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-12 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-13 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-14 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-15 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-16 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-17 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-18 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-19 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-20 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-21 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-22 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-23 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-24 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-25 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-26 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-27 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-28 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-29 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-30 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-31 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-32 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-33 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-34 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-35 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-36 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-37 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-38 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-39 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-40 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-41 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-42 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-43 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-44 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-45 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-46 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-47 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-48 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-49 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-50 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-51 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-52 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-53 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-54 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-55 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-56 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-57 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-58 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-59 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-60 E1P1Q1V1 GLN A.189 GLU C.5 PRO C.8 VAL C.20
4CDW-NA-61 E1Q1 GLN A.189 GLU C.5
4CDW-NA-62 E1Q1 GLN A.189 GLU C.5
4CDW-NA-63 E1Q1 GLN A.189 GLU C.5
4CDW-NA-64 E1Q1 GLN A.189 GLU C.5
4CDW-NA-65 E1Q1 GLN A.189 GLU C.5
4CDW-NA-66 E1Q1 GLN A.189 GLU C.5
4CDW-NA-67 E1Q1 GLN A.189 GLU C.5
4CDW-NA-68 E1Q1 GLN A.189 GLU C.5
4CDW-NA-69 E1Q1 GLN A.189 GLU C.5
4CDW-NA-70 E1Q1 GLN A.189 GLU C.5
4CDW-NA-71 E1Q1 GLN A.189 GLU C.5
4CDW-NA-72 E1Q1 GLN A.189 GLU C.5
4CDW-NA-73 E1Q1 GLN A.189 GLU C.5
4CDW-NA-74 E1Q1 GLN A.189 GLU C.5
4CDW-NA-75 E1Q1 GLN A.189 GLU C.5
4CDW-NA-76 E1Q1 GLN A.189 GLU C.5
4CDW-NA-77 E1Q1 GLN A.189 GLU C.5
4CDW-NA-78 E1Q1 GLN A.189 GLU C.5
4CDW-NA-79 E1Q1 GLN A.189 GLU C.5
4CDW-NA-80 E1Q1 GLN A.189 GLU C.5
4CDW-NA-81 E1Q1 GLN A.189 GLU C.5
4CDW-NA-82 E1Q1 GLN A.189 GLU C.5
4CDW-NA-83 E1Q1 GLN A.189 GLU C.5
4CDW-NA-84 E1Q1 GLN A.189 GLU C.5
4CDW-NA-85 E1Q1 GLN A.189 GLU C.5
4CDW-NA-86 E1Q1 GLN A.189 GLU C.5
4CDW-NA-87 E1Q1 GLN A.189 GLU C.5
4CDW-NA-88 E1Q1 GLN A.189 GLU C.5
4CDW-NA-89 E1Q1 GLN A.189 GLU C.5
4CDW-NA-90 E1Q1 GLN A.189 GLU C.5
4CDW-NA-91 E1Q1 GLN A.189 GLU C.5
4CDW-NA-92 E1Q1 GLN A.189 GLU C.5
4CDW-NA-93 E1Q1 GLN A.189 GLU C.5
4CDW-NA-94 E1Q1 GLN A.189 GLU C.5
4CDW-NA-95 E1Q1 GLN A.189 GLU C.5
4CDW-NA-96 E1Q1 GLN A.189 GLU C.5
4CDW-NA-97 E1Q1 GLN A.189 GLU C.5
4CDW-NA-98 E1Q1 GLN A.189 GLU C.5
4CDW-NA-99 E1Q1 GLN A.189 GLU C.5
4CDW-NA-100 E1Q1 GLN A.189 GLU C.5
4CDW-NA-101 E1Q1 GLN A.189 GLU C.5
4CDW-NA-102 E1Q1 GLN A.189 GLU C.5
4CDW-NA-103 E1Q1 GLN A.189 GLU C.5
4CDW-NA-104 E1Q1 GLN A.189 GLU C.5
4CDW-NA-105 E1Q1 GLN A.189 GLU C.5
4CDW-NA-106 E1Q1 GLN A.189 GLU C.5
4CDW-NA-107 E1Q1 GLN A.189 GLU C.5
4CDW-NA-108 E1Q1 GLN A.189 GLU C.5
4CDW-NA-109 E1Q1 GLN A.189 GLU C.5
4CDW-NA-110 E1Q1 GLN A.189 GLU C.5
4CDW-NA-111 E1Q1 GLN A.189 GLU C.5
4CDW-NA-112 E1Q1 GLN A.189 GLU C.5
4CDW-NA-113 E1Q1 GLN A.189 GLU C.5
4CDW-NA-114 E1Q1 GLN A.189 GLU C.5
4CDW-NA-115 E1Q1 GLN A.189 GLU C.5
4CDW-NA-116 E1Q1 GLN A.189 GLU C.5
4CDW-NA-117 E1Q1 GLN A.189 GLU C.5
4CDW-NA-118 E1Q1 GLN A.189 GLU C.5
4CDW-NA-119 E1Q1 GLN A.189 GLU C.5
4CDW-NA-120 E1Q1 GLN A.189 GLU C.5