Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening

PDB ID: 4DHQ
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2012-01-30
Classification: PROTEIN BINDING/INHIBITOR
Keywords: ADAPTER PROTEIN, PHOSPHOPROTEIN BINDING, PROTEIN BINDING-INHIBITOR complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.75
R-value: 0.149
Metal site idBound amino acidsBound ligands IDs
4DHQ-MG-1 E1K1Q1 GLN A.8 GLU A.80 HOH A.747 HOH A.748 HOH A.829 LYS A.77
4DHQ-MG-2 E1K1Q1 GLN A.8 GLU A.80 HOH A.747 HOH A.748 HOH A.829 LYS A.77