Human DNA polymerase eta inserting dCMPNPP opposite GG template (GG0b).

PDB ID: 4DL3
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2012-02-05
Classification: TRANSFERASE/DNA/INHIBITOR
Keywords: cisplatin, chemoresistence, translesion synthesis, human DNA polymerse eta, kinetics, molecular splint, inhibition, DNA distorsion, second TLS polymerase, nucleotidyl transfer reaction, PCNA, nucleus, TRANSFERASE-DNA-INHIBITOR complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.1
R-value: 0.204
Metal site idBound amino acidsBound ligands IDs
4DL3-MG-1 C1D2E1 0KX P.10 ASP A.115 ASP A.13 MET A.14