Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant, complexed with IMP and mycophenolic acid

PDB ID: 4FO4
Gene source organism: Vibrio cholerae O1 biovar El Tor
Expression organism: Escherichia coli Deposition date: 2012-06-20
Classification: OXIDOREDUCTASE
Keywords: structural genomics, IMPDH, IMP, mycophenolic acid, MOA, NIAID, National Institute of Allergy and Infectious Diseases, Center for Structural Genomics of Infectious Diseases, CSGID, OXIDOREDUCTASE
Technique: X-RAY DIFFRACTION
Assembly: 3
Resolution: 2.03
R-value: 0.16518
Metal site idBound amino acidsBound ligands IDs
4FO4-K-1 C1E1G2H1S1 CYS A.307 GLU A.471 GLY A.302 GLY A.304 HIS A.473 SER A.472
4FO4-K-2 C1E1G2H1S1 CYS A.307 GLU A.471 GLY A.302 GLY A.304 HIS A.473 SER A.472
4FO4-K-3 C1E1G2H1S1 CYS A.307 GLU A.471 GLY A.302 GLY A.304 HIS A.473 SER A.472
4FO4-K-4 C1E1G2H1S1 CYS A.307 GLU A.471 GLY A.302 GLY A.304 HIS A.473 SER A.472
4FO4-K-5 C1E1G2S1 CYS B.307 GLU B.471 GLY B.302 GLY B.304 SER B.472
4FO4-K-6 C1E1G2S1 CYS B.307 GLU B.471 GLY B.302 GLY B.304 SER B.472
4FO4-K-7 C1E1G2S1 CYS B.307 GLU B.471 GLY B.302 GLY B.304 SER B.472
4FO4-K-8 C1E1G2S1 CYS B.307 GLU B.471 GLY B.302 GLY B.304 SER B.472