Base pairing mechanism of N2,3-ethenoguanine with dTTP by human polymerase iota

PDB ID: 4FS1
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2012-06-26
Classification: TRANSFERASE/DNA
Keywords: human DNA polymerase iota, DNA polymerase, DNA replication, lesion bypass, 2'-fluoro arabinose, N2, 3-ethenoguanine, dTTP, template, TRANSFERASE-DNA complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.5
R-value: 0.215
Metal site idBound amino acidsBound ligands IDs
4FS1-MG-1 C1I2K1 DC B.12 HOH A.613 ILE A.239 ILE A.242 LYS A.237