Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae complexed with IMP and mycophenolic acid

PDB ID: 4FXS
Gene source organism: Vibrio cholerae O1 biovar El Tor
Expression organism: Escherichia coli Deposition date: 2012-07-03
Classification: OXIDOREDUCTASE
Keywords: structural genomics, IMPDH, IMP, mycophenolic acid, MOA, NIAID, National Institute of Allergy and Infectious Diseases, Center for Structural Genomics of Infectious Diseases, CSGID, OXIDOREDUCTASE
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.24
R-value: 0.1896
Metal site idBound amino acidsBound ligands IDs
4FXS-K-1 C1E1G1H1S1 CYS A.307 GLU A.471 GLY A.304 HIS A.473 SER A.472
4FXS-K-2 C1E1G1H1S1 CYS A.307 GLU A.471 GLY A.304 HIS A.473 SER A.472
4FXS-K-3 C1E1G1H1S1 CYS A.307 GLU A.471 GLY A.304 HIS A.473 SER A.472
4FXS-K-4 C1E1G1H1S1 CYS A.307 GLU A.471 GLY A.304 HIS A.473 SER A.472