Crystal structure of streptogramin group A antibiotic acetyltransferase VatA from Staphylococcus aureus in complex with virginiamycin M1

PDB ID: 4HUS
Gene source organism: Staphylococcus aureus
Expression organism: Escherichia coli Deposition date: 2012-11-03
Classification: TRANSFERASE/ANTIBIOTIC
Keywords: STRUCTURAL GENOMICS, ANTIBIOTIC RESISTANCE, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES (CSGID), NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, XENOBIOTIC ACYLTRANSFERASE (XAT) FAMILY, HEXAPEPTIDE REPEAT ACYLTRANSFERASE, streptogramin group A antibiotic acetyltransferase, STREPTOGRAMIN GROUP A ANTIBIOTICS, STREPTOGRAMIN A, VIRGINIAMYCIN M1, DALFOPRISTIN, ACETYL COENZYME A, COENZYME A, INTRACELLULAR, TRANSFERASE-ANTIBIOTIC complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.3
R-value: 0.1842
Metal site idBound amino acidsBound ligands IDs
4HUS-NA-1 N3 ASN A.164 ASN B.164 ASN C.164 HOH A.422 HOH B.417 HOH C.514