Design and synthesis of thiophene dihydroisoquinolins as novel BACE-1 inhibitors

PDB ID: 4I1C
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2012-11-20
Classification: hydrolase/hydrolase inhibitor
Keywords: Aspartic protease, hydrolase-hydrolase inhibitor complex
Technique: X-RAY DIFFRACTION
Assembly: 2
Resolution: 2.0
R-value: 0.20731
Metal site idBound amino acidsBound ligands IDs
4I1C-ZN-1 H2 HIS A.110 HIS A.150