Complex of Mitochondrial Isocitrate Dehydrogenase R140Q Mutant with AGI-6780 Inhibitor

PDB ID: 4JA8
Gene source organism: Homo sapiens
Expression organism: None Deposition date: 2013-02-18
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Keywords: protein-inhibitor complex, metabolic enzyme oncometabolite, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.55
R-value: 0.1816
Metal site idBound amino acidsBound ligands IDs
4JA8-CA-1 D3 ASP A.314 ASP A.318 ASP B.291 HOH A.871 HOH B.601 HOH B.602
4JA8-CA-2 D3 ASP A.291 ASP B.314 ASP B.318 HOH A.601 HOH B.603 HOH B.819 HOH B.847