Crystal structure of the catalytic domain of botulinum neurotoxin BoNT/A C134S mutant with covalent inhibitor that modifies Cys-165 causing disorder in 166-174 stretch

PDB ID: 4KS6
Gene source organism: Clostridium botulinum A
Expression organism: Escherichia coli Deposition date: 2013-05-17
Classification: HYDROLASE/HYDROLASE INHIBITOR
Keywords: Clostridial neurotoxin zinc protease, Peptidase_M27, SNAP 25, covalent inhibition, HYDROLASE-HYDROLASE INHIBITOR complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.79
R-value: 0.19255
Metal site idBound amino acidsBound ligands IDs
4KS6-ZN-1 E1X1 DPP B.2 GLU A.262