Crystal structure of the catalytic domain of botulinum neurotoxin BoNT/A C134S mutant with covalent inhibitor that modifies Cys-165 causing disorder in 167-174 stretch

PDB ID: 4KTX
Gene source organism: Clostridium botulinum A
Expression organism: Escherichia coli Deposition date: 2013-05-21
Classification: HYDROLASE/HYDROLASE INHIBITOR
Keywords: Clostridial neurotoxin zinc protease, Peptidase_M27, SNAP 25, covalent inhibition, HYDROLASE-HYDROLASE INHIBITOR complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.59
R-value: 0.202
Metal site idBound amino acidsBound ligands IDs
4KTX-ZN-1 H2X1 DPP B.2 HIS A.223 HIS A.227