Crystal Structure Analysis of human IDH1 mutants in complex with NADP+ and Ca2+/alpha-Ketoglutarate

PDB ID: 4L04
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2013-05-30
Classification: OXIDOREDUCTASE
Keywords: cytosolic, OXIDOREDUCTASE
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.866
R-value: 0.1999
Metal site idBound amino acidsBound ligands IDs
4L04-CA-1 D3 AKG A.501 ASP A.275 ASP A.279 ASP B.252
4L04-CA-2 D3 AKG B.501 ASP A.252 ASP B.275 ASP B.279 HOH B.611