Crystal Structure Analysis of human IDH1 mutants in complex with NADP+ and Ca2+/alpha-Ketoglutarate

PDB ID: 4L06
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2013-05-30
Classification: OXIDOREDUCTASE
Keywords: cytosolic, OXIDOREDUCTASE
Technique: X-RAY DIFFRACTION
Assembly: 2
Resolution: 2.282
R-value: 0.2241
Metal site idBound amino acidsBound ligands IDs
4L06-CA-1 D3 AKG C.503 ASP C.275 ASP C.279 ASP D.252 HOH C.610
4L06-CA-2 D3 AKG D.503 ASP C.252 ASP D.275 ASP D.279