Humanized rat apo-COMT in complex with a ureido-benzamidine

PDB ID: 4PYQ
Gene source organism: Rattus norvegicus
Expression organism: Escherichia coli Deposition date: 2014-03-27
Classification: Transferase/transferase inhibitor
Keywords: METHYLTRANSFERASE, NEUROTRANSMITTER DEGRADATION, ALTERNATIVE INITIATION, CATECHOLAMINE METABOLISM, CELL MEMBRANE, MAGNESIUM, MEMBRANE, METAL-BINDING, PHOSPHOPROTEIN, SIGNAL-ANCHOR, TRANSMEMBRANE ANCHOR, ENZYME MECHANISM, CONFORMATIONAL CHANGE, Transferase-transferase inhibitor complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.39
R-value: 0.132
Metal site idBound amino acidsBound ligands IDs
4PYQ-NA-1 E1F1R1S1V1 ARG A.227 GLU B.242 HOH B.401 PHE A.232 SER A.229 VAL A.226
4PYQ-NA-2 E1F1R1S1V1 ARG B.227 GLU A.242 HOH A.489 PHE B.232 SER B.229 VAL B.226