yCP beta5-C52F mutant in complex with carfilzomib

PDB ID: 4QWR
Gene source organism: Saccharomyces cerevisiae
Expression organism: SACCHAROMYCES CEREVISIAE Deposition date: 2014-07-17
Classification: HYDROLASE/HYDROLASE INHIBITOR
Keywords: Cancer, Proteasome, Bortezomib, Drug Resistance, Binding Analysis, HYDROLASE-HYDROLASE INHIBITOR complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.9
R-value: 0.18061
Metal site idBound amino acidsBound ligands IDs
4QWR-MG-1 A1D2S1 ALA K.165 ASP K.168 ASP W.204 SER K.171
4QWR-MG-2 D1Q1 ASP N.51 GLN H.91
4QWR-MG-3 D2I1S1 ASP L.222 ASP V.166 ILE V.163 SER V.169
4QWR-MG-4 A1D2 ALA Y.165 ASP I.204 ASP Y.168