yCP beta5-M45T mutant in complex with the epoxyketone inhibitor ONX 0914

PDB ID: 4QZ1
Gene source organism: Saccharomyces cerevisiae
Expression organism: SACCHAROMYCES CEREVISIAE Deposition date: 2014-07-27
Classification: HYDROLASE/HYDROLASE INHIBITOR
Keywords: Cancer, Proteasome, Bortezomib, Drug Resistance, Binding Analysis, HYDROLASE-HYDROLASE INHIBITOR complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 3.0
R-value: 0.17599
Metal site idBound amino acidsBound ligands IDs
4QZ1-MG-1 A1D2S1 ALA K.165 ASP K.168 ASP W.204 SER K.171
4QZ1-MG-2 A1D2S1 ALA Y.165 ASP I.204 ASP Y.168 SER Y.171