yCP beta5-A49V mutant in complex with the epoxyketone inhibitor ONX 0914

PDB ID: 4QZ3
Gene source organism: Saccharomyces cerevisiae
Expression organism: SACCHAROMYCES CEREVISIAE Deposition date: 2014-07-27
Classification: HYDROLASE/HYDROLASE INHIBITOR
Keywords: Cancer, Proteasome, Bortezomib, Drug Resistance, Binding Analysis, HYDROLASE-HYDROLASE INHIBITOR complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.8
R-value: 0.18054
Metal site idBound amino acidsBound ligands IDs
4QZ3-MG-1 A1D2S1 ALA K.165 ASP K.168 ASP W.204 SER K.171
4QZ3-MG-2 D2I1 ASP L.222 ASP V.166 ILE V.163
4QZ3-MG-3 A1D2S1 ALA Y.165 ASP I.204 ASP Y.168 HOH Y.401 SER Y.171