Ligand-induced aziridine-formation at subunit beta5 of the yeast 20S proteasome

PDB ID: 4R17
Gene source organism: Saccharomyces cerevisiae S288c
Expression organism: None Deposition date: 2014-08-04
Classification: HYDROLASE/HYDROLASE INHIBITOR
Keywords: Proteasome, Drug Development, Binding Analysis, Umpolung, Crosslink, HYDROLASE-HYDROLASE INHIBITOR complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.1
R-value: 0.185
Metal site idBound amino acidsBound ligands IDs
4R17-MG-1 A1D2S1 HOH H.484 HOH N.304 HOH N.319 HOH N.323 HOH N.402
4R17-MG-2 D2I1S1 HOH I.455 HOH Y.403
4R17-MG-3 A1D2S1 ALA K.165 ASP K.168 ASP W.204 HOH K.409 SER K.171