Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in complex with norfluoxetine

PDB ID: 4XDK
Gene source organism: Homo sapiens
Expression organism: Spodoptera frugiperda Deposition date: 2014-12-19
Classification: TRANSPORT PROTEIN
Keywords: TRANSPORT PROTEIN, OUTWARD RECTIFICATION, MEMBRANE PROTEIN, K2P, Structural Genomics, Structural Genomics Consortium, SGC
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 3.6
R-value: 0.2476
Metal site idBound amino acidsBound ligands IDs
4XDK-K-1 G4 GLY A.174 GLY A.283 GLY B.174 GLY B.283
4XDK-K-2 I2T4V2 ILE A.173 ILE B.173 THR A.172 THR A.281 THR B.172 THR B.281 VAL A.282 VAL B.282
4XDK-K-3 T4 THR A.172 THR A.281 THR B.172 THR B.281