Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin analogue, RC177, and manganese

PDB ID: 4Y6P
Gene source organism: Plasmodium falciparum 3D7
Expression organism: Escherichia coli BL21(DE3) Deposition date: 2015-02-13
Classification: OXIDOREDUCTASE
Keywords: enzyme-inhibitor complex, MEP pathway, isoprenoid biosynthesis, oxidoreductase
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.9
R-value: 0.16498
Metal site idBound amino acidsBound ligands IDs
4Y6P-CA-1 D1L1Q1 ASP A.242 GLN B.239 HOH A.691 HOH A.714 HOH B.728 HOH B.737 LEU B.241