Mutant Human DNA Polymerase Eta Q38A/R61A Inserting dCTP Opposite an 8-Oxoguanine Lesion

PDB ID: 4YP3
Gene source organism: Homo sapiens
Expression organism: Escherichia coli 'BL21-Gold(DE3)pLysS AG' Deposition date: 2015-03-12
Classification: Transferase/DNA
Keywords: Human DNA polymerase eta Q38A/R61A mutation 8-oxoguanine dCTP, Transferase-DNA complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.89
R-value: 0.1685
Metal site idBound amino acidsBound ligands IDs
4YP3-CA-1 D2E1T1 ASP A.115 ASP A.13 DCP A.501 DT P.8 GLU A.116 HOH A.875