Crystal structure of the catalytic domain of botulinum neurotoxin serotype A with a Novel Cyclic Peptide Inhibitor

PDB ID: 4ZJX
Gene source organism: Clostridium botulinum
Expression organism: Escherichia coli Deposition date: 2015-04-29
Classification: HYDROLASE/HYDROLASE INHIBITOR
Keywords: catalytic domain, Zn Endopeptidase, BoNT/A light chain, Bio-warfare agent, Cyclic Peptide Inhibitor, Protease, HYDROLASE-HYDROLASE INHIBITOR complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.94
R-value: 0.177
Metal site idBound amino acidsBound ligands IDs
4ZJX-ZN-1 H2X1 DAB B.197 HIS A.223 HIS A.227