Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the complex with IMP and the inhibitor Q67

PDB ID: 4ZQO
Gene source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Expression organism: ESCHERICHIA COLI Deposition date: 2015-05-10
Classification: Oxidoreductase/Oxidoreductase inhibitor
Keywords: IMPDH, delta CBS, Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID, Oxidoreductase-Oxidoreductase inhibitor complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.75
R-value: 0.153
Metal site idBound amino acidsBound ligands IDs
4ZQO-K-1 C1E1G2S1 CYS A.341 GLU A.511 GLY A.336 GLY A.338 SER A.512
4ZQO-K-2 C1E1G2S1 CYS A.341 GLU A.511 GLY A.336 GLY A.338 SER A.512
4ZQO-K-3 C1E1G2S1 CYS A.341 GLU A.511 GLY A.336 GLY A.338 SER A.512
4ZQO-K-4 C1E1G2S1 CYS A.341 GLU A.511 GLY A.336 GLY A.338 SER A.512