Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the complex with IMP and the inhibitor MAD1

PDB ID: 4ZQP
Gene source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Expression organism: ESCHERICHIA COLI Deposition date: 2015-05-10
Classification: Oxidoreductase/Oxidoreductase inhibitor
Keywords: IMPDH, delta CBS, MAD1, Structural Genomics, Center for Membrane Proteins of Infectious Diseases, Center for Structural Genomics of Infectious Diseases, CSGID, Oxidoreductase-Oxidoreductase inhibitor complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.9
R-value: 0.143
Metal site idBound amino acidsBound ligands IDs
4ZQP-K-1 C1E1G2H1S1 CYS A.341 GLU A.511 GLY A.336 GLY A.338 HIS A.513 SER A.512
4ZQP-K-2 C1E1G2H1S1 CYS A.341 GLU A.511 GLY A.336 GLY A.338 HIS A.513 SER A.512
4ZQP-K-3 C1E1G2H1S1 CYS A.341 GLU A.511 GLY A.336 GLY A.338 HIS A.513 SER A.512
4ZQP-K-4 C1E1G2H1S1 CYS A.341 GLU A.511 GLY A.336 GLY A.338 HIS A.513 SER A.512