Yeast 20S proteasome beta5-D17N mutant in complex with Carfilzomib; Propeptide expressed in trans

PDB ID: 5CZ9
Gene source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Expression organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) Deposition date: 2015-07-31
Classification: HYDROLASE/HYDROLASE INHIBITOR
Keywords: HYDROLASE-HYDROLASE INHIBITOR complex, Proteasome, Mutant, Inhibitor, Binding Analysis
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.8
R-value: 0.19886
Metal site idBound amino acidsBound ligands IDs
5CZ9-MG-1 A1D2S1 ALA Y.165 ASP I.204 ASP Y.168 SER Y.171
5CZ9-MG-2 A1D2S1 ALA K.165 ASP K.168 ASP W.204 SER K.171
5CZ9-MG-3 D2I1 ASP L.222 ASP V.166 ILE V.163