Yeast 20S proteasome beta5-T1C mutant in complex with Carfilzomib

PDB ID: 5D0V
Gene source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Expression organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) Deposition date: 2015-08-03
Classification: HYDROLASE/HYDROLASE INHIBITOR
Keywords: HYDROLASE-HYDROLASE INHIBITOR complex, Proteasome, Mutant, Inhibitor, Binding Analysis
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.9
R-value: 0.19293
Metal site idBound amino acidsBound ligands IDs
5D0V-MG-1 D1N1Q1 ASN N.92 ASP N.51 GLN H.91
5D0V-MG-2 A1D2S1 ALA Y.165 ASP I.204 ASP Y.168 SER Y.171
5D0V-MG-3 A1D2 ALA K.165 ASP K.168 ASP W.204
5D0V-MG-4 D2I1 ASP L.222 ASP V.166 ILE V.163