Crystal Structure of Human DNA Polymerase Eta Inserting dGMPNPP Opposite O4-Ethylthymidine

PDB ID: 5DQH
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2015-09-14
Classification: Transferase/DNA
Keywords: Catalytic Domain, DNA Damage, DNA-Directed DNA Polymerase, Guanosine Triphosphate, Y-family polymerase, trans-lesion synthesis (TLS), DNA Binding, O4-Alkylthymidine, O4-Ethylthymidine, Transferase-DNA complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.99
R-value: 0.1612
Metal site idBound amino acidsBound ligands IDs
5DQH-MG-1 D2E1T1 ASP A.115 ASP A.13 DT P.8 GLU A.116 HOH A.694 XG4 A.501