Crystal Structure of Human DNA Polymerase Eta Extending an O4-Ethylthymidine : dA Pair By Inserting dCTP Opposite dG

PDB ID: 5DQI
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2015-09-14
Classification: Transferase/DNA
Keywords: Catalytic Domain, DNA Damage, DNA-Directed DNA Polymerase, Adenosine Triphosphate, Y-family polymerase, trans-lesion synthesis (TLS), DNA Binding, O4-Alkylthymidine, O4-Ethylthymidine, Transferase-DNA complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.3
R-value: 0.20388
Metal site idBound amino acidsBound ligands IDs
5DQI-CA-1 C1D2E1 ASP A.115 ASP A.13 DC P.9 DCP A.501 GLU A.116 HOH A.639