Yeast 20S proteasome beta1-T1A beta2-T1A double mutant in complex with Carfilzomib

PDB ID: 5FGI
Gene source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Expression organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) Deposition date: 2015-12-20
Classification: HYDROLASE/HYDROLASE INHIBITOR
Keywords: HYDROLASE-HYDROLASE INHIBITOR complex, Proteasome, Mutant, Inhibitor, Binding Analysis
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.9
R-value: 0.18591
Metal site idBound amino acidsBound ligands IDs
5FGI-MG-1 A1D2S1 ALA Y.165 ASP I.204 ASP Y.168 SER Y.171
5FGI-MG-2 A1D2S1 ALA K.165 ASP K.168 ASP W.204 SER K.171