STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE In COMPLEX WITH A DNA aptamer and an Alpha-carboxy nucleoside phosphonate inhibitor (alpha-CNP)

PDB ID: 5HRO
Gene source organism: Human immunodeficiency virus type 1 group M subtype B (isolate BH10)
Expression organism: Escherichia coli Deposition date: 2016-01-23
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Keywords: RT, DNA APTAMER, NCRTI, nucleotide-competing RT inhibitor, 2-O-METHYLCYTIDINE, P51, P66, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.75
R-value: 0.2348
Metal site idBound amino acidsBound ligands IDs
5HRO-MG-1 D3G1 3JY A.603 ASP A.110 ASP A.185 ASP A.186 DG E.37