Efficient targeting of the asialoglycoprotein receptor by polyvalent display of a compact galactoseamine mimic

PDB ID: 5JPV
Gene source organism: Homo sapiens
Expression organism: Escherichia coli-Pichia pastoris shuttle vector pPpARG4 Deposition date: 2016-05-04
Classification: SIGNALING PROTEIN
Keywords: asialoglycoprotein receptor, carbohydrates, liver targeting, SIGNALING PROTEIN
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.9
R-value: 0.19281
Metal site idBound amino acidsBound ligands IDs
5JPV-CA-1 D2E1N1Q1X1 ASN A.264 ASP A.241 ASP A.265 GAL C.2 GLN A.239 GLU A.252
5JPV-CA-2 D2E1N1Q1X1 ASN B.264 ASP B.241 ASP B.265 GAL D.2 GLN B.239 GLU B.252