Yeast 20S proteasome with human beta5c (1-138) and human beta6 (99-132) in complex with epoxyketone inhibitor 14

PDB ID: 5L61
Gene source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Expression organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) Deposition date: 2016-05-28
Classification: HYDROLASE/HYDROLASE INHIBITOR
Keywords: HYDROLASE-HYDROLASE INHIBITOR complex, Proteasome, Mutant, Inhibitor, Binding Analysis
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.8
R-value: 0.17877
Metal site idBound amino acidsBound ligands IDs
5L61-MG-1 A1D2S1 ALA Y.164 ASP I.204 ASP Y.167 SER Y.170
5L61-MG-2 A1D2S1 ALA K.164 ASP K.167 ASP W.204 SER K.170
5L61-MG-3 D2I1S1 ASP L.222 ASP V.166 ILE V.163 SER V.169