Dissociation of biochemical and antiretroviral activities of Integrase-LEDGF Allosteric Inhibitors revealed by resistance of A125 polymorphic HIV-1

PDB ID: 5OI2
Gene source organism: Human immunodeficiency virus 1
Expression organism: Escherichia coli Deposition date: 2017-07-18
Classification: VIRAL PROTEIN
Keywords: HIV-1, Integrase, Catalytic core domain, VIRAL PROTEIN
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.2
R-value: 0.17412
Metal site idBound amino acidsBound ligands IDs
5OI2-MG-1 Q1Y1 HOH A.434 ILE A.84
5OI2-MG-2 Q1Y1 HOH A.434 ILE A.84