Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with IMP and the inhibitor P225

PDB ID: 5UQF
Gene source organism: Campylobacter jejuni subsp. jejuni
Expression organism: Escherichia coli Deposition date: 2017-02-08
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Keywords: IMPDH, TIM barrel, delta CBS, Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Technique: X-RAY DIFFRACTION
Assembly: 4
Resolution: 2.73
R-value: 0.1746
Metal site idBound amino acidsBound ligands IDs
5UQF-K-1 C1E1G2H1S1 CYS A.301 GLU A.465 GLY A.296 GLY A.298 HIS A.467 SER A.466
5UQF-K-2 C1E1G2H1S1 CYS A.301 GLU A.465 GLY A.296 GLY A.298 HIS A.467 SER A.466
5UQF-K-3 C1E1G2H1S1 CYS A.301 GLU A.465 GLY A.296 GLY A.298 HIS A.467 SER A.466
5UQF-K-4 C1E1G2H1S1 CYS A.301 GLU A.465 GLY A.296 GLY A.298 HIS A.467 SER A.466
5UQF-K-5 C1E1G2H1S1 CYS A.301 GLU A.465 GLY A.296 GLY A.298 HIS A.467 SER A.466
5UQF-K-6 C1E1G2H1S1 CYS A.301 GLU A.465 GLY A.296 GLY A.298 HIS A.467 SER A.466
5UQF-K-7 C1E1G2H1S1 CYS A.301 GLU A.465 GLY A.296 GLY A.298 HIS A.467 SER A.466
5UQF-K-8 C1E1G2H1S1 CYS A.301 GLU A.465 GLY A.296 GLY A.298 HIS A.467 SER A.466