Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with IMP and the inhibitor P200

PDB ID: 5UUZ
Gene source organism: Bacillus anthracis
Expression organism: Escherichia coli Deposition date: 2017-02-17
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Keywords: IMPDH, TIM barrel, delta CBS, Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Technique: X-RAY DIFFRACTION
Assembly: 2
Resolution: 2.5
R-value: 0.2227
Metal site idBound amino acidsBound ligands IDs
5UUZ-K-1 C1E1G2S1 CYS F.308 GLU E.470 GLY F.303 GLY F.305 SER E.471
5UUZ-K-2 C1E1G2S1 CYS E.308 GLU G.470 GLY E.303 GLY E.305 SER G.471
5UUZ-K-3 E1G2H1S1 GLU F.470 GLY H.303 GLY H.305 HIS F.472 SER F.471
5UUZ-K-4 C1E1G2S1 CYS G.308 GLU H.470 GLY G.303 GLY G.305 SER H.471