Novel Binding Modes of Inhibition of Wild-Type IDH1: Allosteric Inhibition with Cmpd2

PDB ID: 6BKY
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2017-11-09
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Keywords: dehydrogenase, inhibitor, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE inhibitor complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.17
R-value: 0.185
Metal site idBound amino acidsBound ligands IDs
6BKY-MG-1 D3 ASP C.252 ASP D.275 ASP D.279
6BKY-MG-2 D3 ASP C.275 ASP C.279 ASP D.252