Novel Modes of Inhibition of Wild-Type IDH1: Direct Covalent Modification of His315 with Cmpd13

PDB ID: 6BL1
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2017-11-09
Classification: oxidoreductase/oxidoreductase inhibitor
Keywords: dehydrogenase, inhibitor, oxidoreductase-oxidoreductase inhibitor complex
Technique: X-RAY DIFFRACTION
Assembly: 2
Resolution: 2.017
R-value: 0.183
Metal site idBound amino acidsBound ligands IDs
6BL1-CA-1 D2 ASP C.252 ASP C.275 HOH C.614 HOH C.669 ICT C.502
6BL1-CA-2 D2 ASP C.252 ASP C.275 HOH C.614 HOH C.669 ICT C.502