Crystal Structure of Human DNA polymerase kappa in complex with DNA containing the major cisplatin lesion

PDB ID: 6BRX
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2017-12-01
Classification: REPLICATION
Keywords: Cisplatin, DNA adduct, translesion DNA synthesis, polymerase kappa, chemoresistance, REPLICATION
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.8
R-value: 0.21359
Metal site idBound amino acidsBound ligands IDs
6BRX-MG-1 A1I1R1V1 ARG A.352 DA C.12 ILE A.357 VAL A.354
6BRX-MG-2 C1D1E1 0KX A.604 ASP A.198 DC C.13 GLU A.199