Crystal Structure of Human DNA polymerase kappa in complex with DNA containing the major cisplatin lesion

PDB ID: 6BS1
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2017-12-01
Classification: REPLICATION
Keywords: Cisplatin, DNA adduct, translesion DNA synthesis, polymerase kappa, chemoresistance, REPLICATION
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 3.15
R-value: 0.2442
Metal site idBound amino acidsBound ligands IDs
6BS1-MG-1 C1I1R1V1 ARG A.352 DC C.12 HOH C.101 ILE A.357 VAL A.354
6BS1-MG-2 C1D1E1 ASP A.107 DC C.13 DZ4 A.609 GLU A.199