Yeast 20S proteasome beta2-G45A mutant in complex with carfilzomib

PDB ID: 6HWE
Gene source organism: Saccharomyces cerevisiae S288C
Expression organism: Saccharomyces cerevisiae S288C Deposition date: 2018-10-11
Classification: HYDROLASE
Keywords: Proteasome, Mutant, Inhibitor, Binding Analysis, HYDROLASE
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.3
R-value: 0.20435
Metal site idBound amino acidsBound ligands IDs
6HWE-MG-1 A1D2S1 ALA Y.165 ASP I.204 ASP Y.168 HOH Y.444 SER Y.171
6HWE-MG-2 A1D2H1 ALA K.165 ASP K.168 ASP W.204 HIS K.166
6HWE-MG-3 D2I1S1 ASP L.222 ASP V.166 ILE V.163 SER V.169